Bioactivity | Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of drug resistance[1]. |
Target | Mitochondrial cytochrome bc1 |
Name | Inz-5 |
CAS | 1585214-21-6 |
Formula | C18H14F4N6 |
Molar Mass | 390.34 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Reference | [1]. Vincent BM, et al. A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. Cell Chem Biol. 2016 Aug 18;23(8):978-991. |