Insulin-like growth factor II_product_DataBase

Bioactivity	Insulin-like growth factor II (IGF-2) is the principal somatomedin of human serum. Insulin-like growth factor II exerts permissive and direct effects on neurite outgrowth and enhances survival of sympathetic and sensory neurons[1][2].
Invitro	Insulin-like growth factor II (IGF-2) (1-100 ng/mL; 24 h) 在 SH-SY5Y 细胞中以剂量依赖的方式显著增加了轴突承载细胞的百分比[2]。Insulin-like growth factor II (IGF-2) (1-100 ng/mL; 24 h) 和 IGFBP2 联合治疗增强了早期 IGF-1R 相关信号[2]。 Western Blot Analysis[2] Cell Line:
Name	Insulin-like growth factor II
CAS	67763-97-7
Sequence	Ala-Tyr-Arg-Pro-Ser-Glu-Thr-Leu-Cys-Gly-Gly-Glu-Leu-Val-Asp-Thr-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Ser-Arg-Pro-Ala-Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg-Gly-Ile-Val-Glu-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Ala-Leu-Leu-Glu-Thr-Tyr-Cys-Ala-Thr-Pro-Ala-Lys-Ser-Glu (Disulfide bridge:Cys9-Cys47;Cys21-Cys60;Cys46-Cys51)
Shortening	AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE (Disulfide bridge:Cys9-Cys47;Cys21-Cys60;Cys46-Cys51)
Formula	C321H505N93O161S6
Molar Mass	7469.33
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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