| Bioactivity | InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM[1]. |
| Target | 96 nM (InhA) |
| CAS | 952588-17-9 |
| Formula | C17H18Cl2O2 |
| Molar Mass | 325.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Freundlich JS, et al., Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis. ChemMedChem. 2009 Feb;4(2):241-8. |
InhA-IN-7
CAS: 952588-17-9 F: C17H18Cl2O2 W: 325.23
InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein
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