PeptideDB

InhA-IN-2

CAS: 2428737-43-1 F: C16H15ClN2O2S2 W: 366.89

InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM
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Bioactivity InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM[1].
Target IC50: 0.31 μM (InhA)
Invitro InhA-IN-2 (Compound 23) (200 µM, 48h) inhibits mycolic acid synthesis (33% growth inhibition) in M. tuberculosis H37Ra[1].
Name InhA-IN-2
CAS 2428737-43-1
Formula C16H15ClN2O2S2
Molar Mass 366.89
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Sabbah M, et al. Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. J Med Chem. 2020 May 14;63(9):4749-4761.