Bioactivity | Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities[1]. |
Target | EC50: 2.46 µM (influenza virus); CC50: >200 µM (influenza virus) |
Name | Influenza virus-IN-1 |
CAS | 108729-21-1 |
Formula | C16H17NO5 |
Molar Mass | 303.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liao Y, et al. Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PAN endonuclease. Eur J Med Chem. 2020 Mar 1;189:112048. |