Influenza A virus-IN-15_product_DataBase

Bioactivity	Influenza A virus-IN-15 (Compound 9b), a quinoline derivative, is a broad-spectrum inhibitor of influenza A viruses with acceptable cytotoxicity (IC50: 0.88-6.33 μM). Influenza A virus-IN-15 can inhibit the transcription and replication of viral RNA and is used in research for its antiviral effects against influenza A viruses (IAV)[1].
Target	IC50: 0.88 μM (IAV).
Invitro	Influenza A virus-IN-15 (Compound 9b) 能抑制 IAV 的活性，其 IC50 值为 0.88 μM[1]。Influenza A virus-IN-15 以剂量非依赖的方式有效抑制了 A/Puerto Rico/8/34(H1N1)、A/Aichi/2/1968(X31)(H3N2)、B/Brisbane/60/2008(B/Victoria) 和 B/Phuket/3073/2013(B/Yamagata) 毒株的感染，其 IC50 值分别为 3.57 μM、4.66 μM、5.16 μM 和 6.33 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Influenza A virus-IN-15 相关抗体:
Formula	C29H30N6O3
Molar Mass	510.59
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Li H, Zhao J, et al. Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 130081.

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