| Bioactivity | Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research[1][2][3]. |
| Invitro | Indomethacin (Indometacin) sodium hydrateis (0-150 μM; 24 hours; 3LL-D122 cells) has anticancer activity in vitro[2].Indomethacin (Indometacin) sodium hydrateis (0-1000 μM) protects the host cells from damage caused by the virus through activates PKR, resulting in elF2α phosphorylation, and in turn shutting of translation of viral protein and inhibiting replication of the virus (IC50=2 μM)[3]. Cell Viability Assay[2] Cell Line: |
| Name | Indomethacin sodium hydrate |
| CAS | 74252-25-8 |
| Formula | C19H21ClNNaO7 |
| Molar Mass | 433.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
Indomethacin sodium hydrate
CAS: 74252-25-8 F: C19H21ClNNaO7 W: 433.82
Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2inhibitor with IC50 values of 18 nM and 26 nM
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