| Bioactivity | Indomethacin N-octyl amide (Compound 2) is a potent and selective COX-2 inhibitor with an IC50 of 40 nM. Indomethacin N-octyl amide shows >1000-fold selectivity against COX-1 (IC50 of 66 µM)[1]. |
| CAS | 282728-65-8 |
| Formula | C27H33ClN2O3 |
| Molar Mass | 469.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yumi Yamamoto, et al. ¹¹C-labeled analogs of indomethacin esters and amides for brain cyclooxygenase-2 imaging: radiosynthesis, in vitro evaluation and in vivo characteristics in mice. Chem Pharm Bull (Tokyo). 2011;59(8):938-46. |
Indomethacin N-octyl amide
CAS: 282728-65-8 F: C27H33ClN2O3 W: 469.02
Indomethacin N-octyl amide (Compound 2) is a potent and selective COX-2 inhibitor with an IC50 of 40 nM. Indomethacin N-
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