| Bioactivity | Imperatoxin A TFA is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. Imperatoxin A TFA is a Ca2+-release channels/ryanodine receptors (RyRs) activator. Imperatoxin A TFA enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell[1]. |
| Sequence | Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32) |
| Shortening | GDCLPHLKRCKADNDCCGKKCKRRGTNAEKRCR (Disulfide bridge:Cys3-Cys17;Cys10-Cys21;Cys16-Cys32) |
| Formula | C148H254N58O45S6.xC2HF3O2 |
| Molar Mass | 3758.35 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Georgina B Gurrola, et al. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca2+-Release Channels/Ryanodine Receptors. Pharmaceuticals (Basel). 2010 Apr 1;3(4):1093-1107. |
Imperatoxin A TFA
CAS: F: C148H254N58O45S6.xC2HF3O2 W: 3758.35 (free base)
Imperatoxin A TFA is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. Imperatoxin A TF
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