| Bioactivity | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research[1][2][3][4]. | |||||||||
| Invitro | Prostacyclin (PGI2) is synthesised in oviductal fluid and enhance the embryo development[1].Iloprost is an PGI2 analog, and affects maturation and developmental competence of bovine oocytes[1]. Iloprost (0.5 μM; 22-24 h) increases blastocyst rates of bovine embryos as well as proportion of expanded blastocysts[1].Iloprost (0.5 μM; 22-24 h) assists maturation rates and cumulus cell expansion of bovine oocytes, and increases the mRNA expression of genes related to cumulus expansion[1].Iloprost (0.5 μM; 22-24 h) reduces the occurrence of apoptosis in COCs and promotes an anti-apoptotic balance in the transcription of genes involved in apoptosis (BAX and BCL2) [1]. RT-PCR[1] Cell Line: | |||||||||
| Name | Iloprost | |||||||||
| CAS | 78919-13-8 | |||||||||
| Formula | C22H32O4 | |||||||||
| Molar Mass | 360.49 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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