Ilmofosine_product_DataBase

Bioactivity	Ilmofosine (BM41440) is a potent and selective protein kinase C inhibitor. Ilmofosine induces cell cycle arrest at the G2 phase. Ilmofosine also is an anti-leishmanial agent[1][2].
Invitro	Ilmofosine 抑制利什曼原虫的无鞭毛体和对锑有抗性的利什曼原虫，ED50 值分别为 3.73、3.46 µM[1]。Ilmofosine (15 µM; 48 h) 诱导 CA46 细胞周期停滞在 G2 期细胞[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Ilmofosine 相关抗体: Cell Cycle Analysis[2] Cell Line:
CAS	83519-04-4
Formula	C26H56NO5PS
Molar Mass	525.77
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Croft SL, et al. Antileishmanial activity of the ether phospholipid ilmofosine. Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):217-9. [2]. Hofmann J, et al. The protein kinase C inhibitor ilmofosine (BM 41 440) arrests cells in G2 phase and suppresses CDC2 kinase activation through a mechanism different from that of DNA damaging agents. Biochem Biophys Res Commun. 1994 Mar 15;199(2):937-43.

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