| Bioactivity | Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively[1][2][3]. | |||||||||
| Invitro | Icatibant (10-30 μM) potentiates angiotensin III, but not angiotensin II (contraction mediated by angiotensin AT1 receptors), and Lys-des-Arg9-bradykinin, but not des-Arg9-bradykinin (effects mediated by the bradykinin B1 receptors)[3]. | |||||||||
| Name | Icatibant | |||||||||
| CAS | 130308-48-4 | |||||||||
| Formula | C59H89N19O13S | |||||||||
| Molar Mass | 1304.52 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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Icatibant
CAS: 130308-48-4 F: C59H89N19O13S W: 1304.52
Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM an
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