| Bioactivity | IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1]. | |||||||||
| Name | IWP-12 | |||||||||
| CAS | 688353-45-9 | |||||||||
| Formula | C18H18N4O2S3 | |||||||||
| Molar Mass | 418.56 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Wang X, et al. The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28;56(6):2700-4. |