| Bioactivity | IRL-1620 is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM. |
| Invitro | IRL-1620 is the most potent and specific ligand for the ETB receptor (KiETA/ KiETB=120,000) as judged by the Ki values for ETA (19 μM) and ETB (16 PM) receptors[1]. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (KiETA/ KiETB=1,900)[1]. |
| Name | IRL-1620 |
| CAS | 142569-99-1 |
| Sequence | {Suc}-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp |
| Shortening | {Suc}-DEEAVYFAHLDIIW |
| Formula | C86H117N17O27 |
| Molar Mass | 1820.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |