| Bioactivity | IRE1α kinase-IN-5 (compound 7) is a potent IRE1α inhibitor with an Ki of 98 nM. IRE1α kinase-IN-5 is the ATP-competitive ligands of IRE1α[1]. |
| Target | Ki: 98 nM (IRE1α) |
| Name | IRE1α kinase-IN-5 |
| Formula | C28H30N6O3S |
| Molar Mass | 530.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feldman HC, et al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156. |