Bioactivity | IRE1a-IN-1 (Compound 10) is an IRE1α inhibitor, with an IC50 of less than 100 nM for XBP1 mRNA. IRE1a-IN-1 can be used for the research of cancer[1]. |
CAS | 3033375-01-5 |
Formula | C20H19F2NO6 |
Molar Mass | 407.36 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jin ZS, et al. Novel tricyclic heterocyclic aldehyde compound for inhibiting IRE1α and pharmaceutical composition containing the compound. WO2024072110A1. |