| Bioactivity | IONIS-GCCRRx (ISIS 426115), a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO)[1]. |
| CAS | 1431900-72-9 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lijiang Shen, et al. Mechanistic understanding for the greater sensitivity of monkeys to antisense oligonucleotide-mediated complement activation compared with humans. J Pharmacol Exp Ther. 2014 Dec;351(3):709-17. [2]. Gaurav Chikara, et al. A Narrative Review of Potential Future Antidiabetic Drugs: Should We Expect More? Indian J Clin Biochem. 2018 Apr;33(2):121-131. |