| Bioactivity | IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R[1]. |
| Name | IN-2-LF |
| CAS | 749879-64-9 |
| Sequence | Ac-Gly-Tyr-{Bal}-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-NHOH |
| Shortening | Ac-GY-{Bal}-RRRRRRRRVLR-NHOH |
| Formula | C81H150N42O17 |
| Molar Mass | 1984.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Peinado JR, et al. Cross-inhibition between furin and lethal factor inhibitors. Biochem Biophys Res Commun. 2004 Aug 27;321(3):601-5. |
IN-2-LF
CAS: 749879-64-9 F: C81H150N42O17 W: 1984.33
IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection
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