| Bioactivity | IMPDH2-IN-4 (compound 2d), a Mycophenolic acid (HY-B0421) analogue, is a selective IMPDH2 inhibitor with a Ki of 1.8 μM. IMPDH2-IN-4 exhibits good cytotoxic activity against osteosarcoma cancer cell lines. IMPDH2-IN-4 possesses a high affinity for VEGFR-2, CDK2, and IMPDH[1]. |
| Formula | C35H34O6Si |
| Molar Mass | 578.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Patamawadee Silalai, et al. Design and Synthesis of Mycophenolic Acid Analogues for Osteosarcoma Cancer Treatment. ACS Bio Med Chem Au, October 17, 2024. |