| Bioactivity | IL-17A modulator-3 (compound 253) is a IL-17A modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC50 value <10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease[1]. |
| Target | IC50: <10 μM (IL-17A/A) |
| Invitro | IL-17A modulator-3 (0-10 μM; 20 h) inhibits IL-17A/A with an IC50 value <10 μM in HEK-Blue IL-17A reporter cell line[1]. |
| Name | IL-17A modulator-3 |
| CAS | 2467732-95-0 |
| Formula | C34H50FN7O4 |
| Molar Mass | 639.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fatheree, Paul R, et al. Amidoamide ligands as IL-17 modulators and their preparation. US20200247785. 2020. |