| Bioactivity | IL-17A inhibitor 4 (Example 449) is a potent IL-17A inhibitor. IL-17A inhibitor 4 inhibits HTRF and NHK cells viability with IC50s of 0.028 and 0.0047 μM, respectively[1]. |
| CAS | 2735650-99-2 |
| Formula | C30H32F4N8O3 |
| Molar Mass | 628.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Douglas BEHENNA, et al. Imidazopyridazines as modulators of il-17. US, WO2021222404. 2021-11-04. |