| Bioactivity | IL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0.66 μM and an IC50 of 1.14 μM[1]. | ||||||||||||
| Name | IL-17A antagonist 1 | ||||||||||||
| CAS | 2205034-18-8 | ||||||||||||
| Formula | C33H41FN6O4 | ||||||||||||
| Molar Mass | 604.71 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Liu S, et al. Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep. 2016 Aug 16;6:30859. |