| Bioactivity | IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. IL-17-IN-3 exhibits no adverse effects in a rat tolerability study after a four-day administration of up to 300 mg/kg/day[1]. |
| Formula | C22H25F6N5O3S |
| Molar Mass | 553.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Juraj Velcicky, et al. Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing. ChemMedChem. 2024 Dec 23:e202400851. |