| Bioactivity | IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs[1]. |
| Name | IKK2-IN-4 |
| CAS | 354811-10-2 |
| Formula | C12H11N3O2S |
| Molar Mass | 261.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Baxter A, et, al. Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2817-22. |
IKK2-IN-4
CAS: 354811-10-2 F: C12H11N3O2S W: 261.30
IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced product
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