| Bioactivity | IK-930 (compound I-32) is a potent and orally active TEAD inhibitor with an EC50 value of <0.1 µM[1]. | ||||||||||||
| Target | TEAD | ||||||||||||
| In Vivo | IK-930 (compound I-32) (10 mg/kg; p.o.) 在 BALB/c 小鼠中表现出良好的药代动力学参数，Cmax 为 1088 ng/mL，AUC 0-last 为 4581 ng*h/mL[1]. | ||||||||||||
| Name | IK-930 | ||||||||||||
| CAS | 2563892-44-2 | ||||||||||||
| Formula | C19H19F3N4O2S | ||||||||||||
| Molar Mass | 424.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Alfredo C. Castro, et al. Tead inhibitors and uses thereof. WO2020243415A2. |