| Bioactivity | IHMT-RAF-128, a highly potent pan-RAF inhibitor. IHMT-RAF-128 shows potent antitumor efficacy in xenograft mouse tumor models without causing any apparent toxicities[1][2]. |
| CAS | 2479289-15-9 |
| Formula | C27H24F3N5O2 |
| Molar Mass | 507.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Olaoba OT, et al. Driver Mutations in Pancreatic Cancer and Opportunities for Targeted Therapy. Cancers (Basel). 2024 May 9;16(10):1808. [2]. Wang A, et al. Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment. Eur J Pharmacol. 2023 Aug 5;952:175752. |
IHMT-RAF-128
CAS: 2479289-15-9 F: C27H24F3N5O2 W: 507.51
IHMT-RAF-128, a highly potent pan-RAF inhibitor. IHMT-RAF-128 shows potent antitumor efficacy in xenograft mouse tumor m
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