Bioactivity | IETD-CHO TFA (Caspase-8-IN-1) is a potent caspase-8 inhibitor[1]. |
Name | IETD-CHO TFA |
Sequence | Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-{CHO} |
Shortening | Ac-AAVALLPAVLLALLAPIET-{CHO} |
Formula | C95H162N20O26.xC2HF3O2 |
Molar Mass | 2000.42 (free acid) |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Joshi SG, et al. Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity. Infect Immun. 2003 Jul;71(7):4127-36. |