| Bioactivity | IDO1/TDO-IN-1 (30) is a potent dual IDO1 (uncompetitive, Ki of 0.23 μM) and TDO (competitive, Ki of 0.73 μM) inhibitor. IDO1/TDO-IN-1 (30) significantly promotes cell apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway[1]. |
| Name | IDO1/TDO-IN-1 |
| CAS | 2379527-72-5 |
| Formula | C21H16O6 |
| Molar Mass | 364.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiangxin Liu, et al. Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase. Eur J Med Chem. 2022 May 5;235:114294. |
IDO1/TDO-IN-1
CAS: 2379527-72-5 F: C21H16O6 W: 364.35
IDO1/TDO-IN-1 (30) is a potent dual IDO1 (uncompetitive, Ki of 0.23 μM) and TDO (competitive, Ki of 0.73 μM) inhibitor
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.