Bioactivity | IDD388 is a selective aldose reductase (ALR2) inhibitor with an IC50 of 30 nM. IDD388 displays selectivity for ALR2 over ALR1 (IC50 of 14 μM)[1]. |
Target | IC50: 30 nM (ALR2) |
Name | IDD388 |
CAS | 314297-26-2 |
Formula | C16H12BrClFNO4 |
Molar Mass | 416.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Holger Steuber, et al. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J Mol Biol. 2008 Jun 20;379(5):991-1016. |