| Bioactivity | ICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in recognizing immune checkpoints[1]. |
| CAS | 1006002-58-9 |
| Formula | C17H14Cl2N2O2 |
| Molar Mass | 349.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Longfei Zhang, et al. "Discovery of ICOS-targeted small molecules using affinity selection mass spectrometry screening." bioRxiv (2024): 2024-08. |
ICOS-IN-1
CAS: 1006002-58-9 F: C17H14Cl2N2O2 W: 349.21
ICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in r
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