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ICI 169369

CAS: 85273-96-7 F: C19H21ClN2S W: 344.90

ICI 169369 is an orally active, specific serotonin and 5-HT2/5-HT1C receptor competitive antagonist. ICI 169369 exhibits
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Bioactivity ICI 169369 is an orally active, specific serotonin and 5-HT2/5-HT1C receptor competitive antagonist. ICI 169369 exhibits Ki values of 1.79 x 10−8 and 1.58 x 10−6 M for 5-HT2 and 5-HT1, respectively[1][2].
CAS 85273-96-7
Formula C19H21ClN2S
Molar Mass 344.90
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. D S Millson, et al. The effects of a 5-HT2 receptor antagonist (ICI 169,369) on changes in waking EEG, pupillary responses and state of arousal in human volunteers. Br J Clin Pharmacol. 1991 Oct;32(4):447-54. [2]. T P Blackburn, et al. In vitro studies with ICI 169,369, a chemically novel 5-HT antagonist. Eur J Pharmacol. 1988 Jun 10;150(3):247-56.