| Bioactivity | IC-1k is a potent HIV-1 inhibitor with EC50 values of 2.69, 97.97 nM for HIV-1 IIIB, HIV-2 ROD, respectively. IC-1k shows cytotoxicity. IC-1k shows antiviral activity[1]. |
| Invitro | IC-1k 靶向 HIV-1 衣壳蛋白 (CA)，破坏早期衣壳-宿主因子相互作用，并促进晚期衣壳错误组装[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> IC-1k 相关抗体: |
| Formula | C27H22F2N4O3S |
| Molar Mass | 520.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu S, et al. "Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency. J Med Chem. 2024 Oct 17. |