PeptideDB

IBG3

CAS: F: C54H57N9O5S2 W: 976.22

IBG3 is a dual-JQ1-containing BET degrader that targets protein degradation via intramolecular bivalent glues. IBG3 is a
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Bioactivity IBG3 is a dual-JQ1-containing BET degrader that targets protein degradation via intramolecular bivalent glues. IBG3 is a BRD2 and BRD4 bifunctional degrader with DC50 values of 8.6 pM and 6.7 pM, respectively[1].
Formula C54H57N9O5S2
Molar Mass 976.22
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Oliver Hsia, et al. Targeted protein degradation via intramolecular bivalent glues. Nature. 2024 Feb 21.