Bioactivity | IBG3 is a dual-JQ1-containing BET degrader that targets protein degradation via intramolecular bivalent glues. IBG3 is a BRD2 and BRD4 bifunctional degrader with DC50 values of 8.6 pM and 6.7 pM, respectively[1]. |
Formula | C54H57N9O5S2 |
Molar Mass | 976.22 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Oliver Hsia, et al. Targeted protein degradation via intramolecular bivalent glues. Nature. 2024 Feb 21. |