| Bioactivity | IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW is able to activate EBV-specific cytotoxic T lymphocytes (CTLs), which are able to recognize and kill EBV-infected cells expressing LMP1. IALYLQQNW plays an important role in the immune response against EBV-associated tumors and can be used in the study of Hodgkin's disease and nasopharyngeal carcinoma[1]. |
| CAS | 610268-80-9 |
| Sequence | Ile-Ala-Leu-Tyr-Leu-Gln-Gln-Asn-Trp |
| Shortening | IALYLQQNW |
| Formula | C55H81N13O14 |
| Molar Mass | 1148.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Duraiswamy, et al. "Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions." Journal of virology 77.13 (2003): 7401-7410. |
IALYLQQNW
CAS: 610268-80-9 F: C55H81N13O14 W: 1148.31
IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1)
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