| Bioactivity | IA9 (human TREM-2 182-190) is a TREM-2 inhibitor , and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model[1]. | ||||||
| Name | IA9 | ||||||
| Sequence | Ile-Phe-Leu-Ile-Lys-Ile-Leu-Ala-Ala | ||||||
| Shortening | IFLIKILAA | ||||||
| Formula | C51H88N10O10 | ||||||
| Molar Mass | 1001.31 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| Reference | [1]. Sigalov AB. Inhibition of TREM-2 Markedly Suppresses Joint Inflammation and Damage in Experimental Arthritis. Int J Mol Sci. 2022;23(16):8857. Published 2022 Aug 9. |