PeptideDB

Hypericin

CAS: 548-04-9 F: C30H16O8 W: 504.44

Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein
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Bioactivity Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis[1][2][3].
Invitro Hypericin (0.25-4 μM; 24 h) inhibits the growth of fibroblasts (Fb), melanocytes (Mc), and keratinocytes (Kc)[2].Hypericin (3 μM; 24 h) treatment can induce cells apoptosis[2]. Cell Viability Assay[2] Cell Line:
Name Hypericin
CAS 548-04-9
Formula C30H16O8
Molar Mass 504.44
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month