| Bioactivity | Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility drugs. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD50 >2.5 g/kg[1]. | |||||||||
| In Vivo | Hydroxypropylmethyl cellulose acetate succinate（2.5 g/kg；p.o.；单剂量）在大鼠无显著急性毒性[1]。Hydroxypropylmethyl cellulose acetate succinate（0.63、1.25、2.5 g/kg；p.o.；每日一次，连续 2 个月，每周 6 天）在大鼠无显著亚慢性毒性[1]。Hydroxypropylmethyl cellulose acetate succinate（1.25 g/kg、2.5 g/kg；口服；每天一次，连续 2 个月，每周 6 天）在大鼠无显著慢性毒性[1]。 | |||||||||
| Name | Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) | |||||||||
| CAS | 71138-97-1 | |||||||||
| Molar Mass | 20-100 (kDa) | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
|||||||||
| Reference | [1]. Hoshi N, et al. Toxicological studies of hydroxypropylmethylcellulose acetate succinate--acute toxicity in rats and rabbits, and subchronic and chronic toxicities in rats. J Toxicol Sci. 1985 Oct;10 Suppl 2:147-85. |
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)
CAS: 71138-97-1 F: W: 20-100 (kDa)
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility dru
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.