PeptideDB

Hydroxymethyl dasatinib

CAS: 910297-58-4 F: C22H26ClN7O3S W: 504.00

Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib (HY-10181), exhibits an IC50 of 46.7nM in K562 CM
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Bioactivity Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib (HY-10181), exhibits an IC50 of 46.7nM in K562 CML cells[1].
Name Hydroxymethyl dasatinib
CAS 910297-58-4
Formula C22H26ClN7O3S
Molar Mass 504.00
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lisa J Christopher, et al. Metabolism and disposition of dasatinib after oral administration to humans. Drug Metab Dispos. 2008 Jul;36(7):1357-64.