Bioactivity | Hydroxylapatite (Hydroxyapatite) (<50 nm) is a natural form of calcium phosphate and is the main mineral component of bones and teeth. Hydroxylapatite (<50 nm) can stimulate the expression and secretion of collagen in primary human dermal fibroblasts. Hydroxylapatite (<50 nm) has good biocompatibility, bioactivity, and bone conductivity, making it suitable for targeted drug or nucleic acid delivery. Hydroxylapatite (<50 nm) can be used in research on osteoarthritis, gout, and atherosclerosis[1][2]. |
Invitro | 将 Hydroxylapatite 悬浮于 0.2 μm 过滤的纯净水中,超声处理并涡旋 5 分钟,以 16,000 g 离心 1 分钟收集。重复该过程五次,以清洗 Hydroxylapatite 颗粒,并在 0.1 M NaCl 中制备 40 mg/mL 的储备悬浮液,然后注入细胞[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Hydroxylapatite (<50 nm) 相关抗体: |
CAS | 1306-06-5 |
Formula | Ca5HO13P3 |
Molar Mass | 502.31 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Rakshit M, et al. Hydroxyapatite Particles Induced Modulation of Collagen Expression and Secretion in Primary Human Dermal Fibroblasts. Int J Nanomedicine. 2020 Jul 13;15:4943-4956. [2]. Yongjia Liu, et al. Hydroxyapatite-Bovine Serum Albumin-Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma. Adv Healthc Mater. 2020 Nov 9;e2000573. |