Bioactivity | Hydroxyethyl disulfide blocks the inhibitory effect of showdomycin on methotrexate-resistant thymidylate synthase and is also protected by its substrate deoxyuridylic acid, preventing inactivation of the antibiotic[1]. |
CAS | 1892-29-1 |
Formula | C4H10O2S2 |
Molar Mass | 154.25 |
Appearance | 液体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Reference | [1]. Kalman T I. Inhibition of thymidylate synthetase by showdomycin and its 5′-phosphate. Biochemical and Biophysical Research Communications, 1972, 49(4): 1007-1013. |