Hydroxy-α-sanshool_product_DataBase

CAS: 83883-10-7 F: C16H25NO2 W: 263.38

Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s o

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 µM, respectively. Hydroxy-α-sanshool can be used for pain research[1][2].
Invitro	Hydroxy-α-sanshool (0-10 mM; 20 s) induces inward currents in cultured DRG neuron[2].Hydroxy-α-sanshool (1 mM; 0-1 min) increases intracellular Ca2+ in cultured DRG neuron[2]. Cell Viability Assay[2] Cell Line:
Name	Hydroxy-α-sanshool
CAS	83883-10-7
Formula	C16H25NO2
Molar Mass	263.38
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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