| Bioactivity | Human PTHrP-(1-36) is a secretory form of PTHrP with anticalciuric effects. Human PTHrP-(1-36) enhances beta cell function and proliferation. Human PTHrP-(1-36) can be used in the research of humoral hypercalcemia of malignancy (HHM) and hyperparathyroidism[1][3]. |
| Invitro | Human PTHrP-(1-36) (EC50: 0.05 nM) increases intracellular calcium in human epidermal keratinocytes[2].Human PTHrP-(1-36) (100 nM, 24 h) increases human β-cell proliferation[3].Human PTHrP-(1-36) (100 nM, 30 min) enhances insulin secretion in human islets[3].PTHrP-(1-36) (mouse, EC50: 1 nM) induces a rapid Ca2+ response in UMR 106 cells[4]. |
| Name | Human PTHrP-(1-36) |
| CAS | 172867-62-8 |
| Shortening | AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEI |
| Formula | C191H305N59O52 |
| Molar Mass | 4259.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Human PTHrP-(1-36)
CAS: 172867-62-8 F: C191H305N59O52 W: 4259.83
Human PTHrP-(1-36) is a secretory form of PTHrP with anticalciuric effects. Human PTHrP-(1-36) enhances beta cell functi
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