| Bioactivity | Human PD-L1 inhibitor I is a hPD-1 peptide ligand, with a KD of 3.39 μM. Human PD-L1 inhibitor I may disturb the binding of hPD-L1 to hPD-1[1]. | ||||||
| Name | Human PD-L1 inhibitor I | ||||||
| CAS | 2135542-86-6 | ||||||
| Sequence | Phe-Asn-Trp-Asp-Tyr-Ser-Trp-Lys-Ser-Glu-Arg-Leu-Lys-Glu-Ala-Tyr-Asp-Leu | ||||||
| Shortening | FNWDYSWKSERLKEAYDL | ||||||
| Formula | C110H152N26O32 | ||||||
| Molar Mass | 2350.58 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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| Reference | [1]. Tianyu Wang, et al. Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway. J Med Chem. 2019 Feb 28;62(4):1715-1730. |
Human PD-L1 inhibitor I
CAS: 2135542-86-6 F: C110H152N26O32 W: 2350.58
Human PD-L1 inhibitor I is a hPD-1 peptide ligand, with a KD of 3.39 μM. Human PD-L1 inhibitor I may disturb the bindin
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