| Bioactivity | Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90/Aha1 (KDapp=23.5 µM). Hsp90-IN-34 modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1[1]. |
| CAS | 439588-33-7 |
| Formula | C22H14F2N6O |
| Molar Mass | 416.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stiegler S C, et al. A chemical compound inhibiting the Aha1–Hsp90 chaperone complex[J]. Journal of Biological Chemistry, 2017, 292(41): 17073-17083. |
Hsp90-IN-34
CAS: 439588-33-7 F: C22H14F2N6O W: 416.38
Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90
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