| Bioactivity | Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against HPAEC cell line, with the IC50 of 22.67 μM[1]. | ||||||||||||
| CAS | 882582-26-5 | ||||||||||||
| Formula | C23H31N3O4S | ||||||||||||
| Molar Mass | 445.57 | ||||||||||||
| Appearance | 粉末 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Congke Zhao, et al. Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension. Eur J Med Chem. Q12024 Sep 7:279:116855. |
Hsp110-STAT3 interaction-IN-1
CAS: 882582-26-5 F: C23H31N3O4S W: 445.57
Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against
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