Bioactivity | Homo-BacPROTAC7 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis[1]. |
Invitro | Homo-BacPROTAC7 抑制 M. tuberculosis 生长,对 WT 和 ∆clpC2 菌株的 IC50 分别为 0.26 μM 和 0.18 μM[1]。 |
Name | Homo-BacPROTAC7 |
Formula | C103H146N22O18 |
Molar Mass | 1980.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hoi DM, et al. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell. 2023 May 11;186(10):2176-2192.e22. |