| Bioactivity | Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities[1]. |
| Invitro | Hispolon (25 and 50 μM, 24-72 h) inhibits cell viability of U87MG cells[2].Hispolon (25 and 50 μM, 24, 48 h) induces G2/M cell cycle arrest and apoptosis in U87MG cells[2].Hispolon (25 and 50 μM, 2-8 h) decreases the expression of G1–S transition-related protein cyclin D4 but increases the expression of CDK inhibitor p21[2].Hispolon (25 and 50 μM, 24 h) inhibits the migration of U87MG cells[2]. Cell Viability Assay[2] Cell Line: |
| Name | Hispolon |
| CAS | 173933-40-9 |
| Formula | C12H12O4 |
| Molar Mass | 220.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |