Bioactivity | His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA 是 GHRP-1 的代谢物,是一种生长激素释放肽。GHRP-1,或者说 Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2,它具有促进生长激素 (GH) 释放的作用。GHRP-1 在大鼠垂体静态单层细胞中增加 GH 释放,增加 [Ca2+]i 水平,但不影响 cAMP 水平。 | ||||||
Name | His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA | ||||||
Sequence | H-{D-beta-Nal}-AW-{D-Phe}-K-NH2 | ||||||
Shortening | His-{D-beta-Nal}-Ala-Trp-{D-Phe}-Lys-NH2 | ||||||
Formula | C50H58F3N11O8 | ||||||
Molar Mass | 998.06 | ||||||
Appearance | Solid | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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Reference | [1]. Akman MS, et al. Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2) in rat anterior pituitary cells. Endocrinology. 1993 Mar;132(3):1286-91. |