| Bioactivity | Hidrosmin, a flavonoid, is derived from Diosmin (HY-N0178). hidrosmin exerts a beneficial effect against diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and senescence pathways. Hidrosmin can be used for the research of venous insufficiency and diabetes mellitus[1]. |
| Invitro | Hidrosmin (0.1-1 mM) 可下调暴露于高血糖和/或炎症条件下的肾细胞中的细胞因子表达，并调节氧化还原平衡基因[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Hidrosmin 相关抗体: RT-PCR[1] Cell Line: |
| In Vivo | Hidrosmin（300 mg/kg，通过喂食口服，每天一次，持续 7 周）可改善糖尿病小鼠的肾脏损伤[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 115960-14-0 |
| Formula | C30H36O16 |
| Molar Mass | 652.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiménez-Castilla L, et al. Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy. Antioxidants (Basel). 2021 Nov 29;10(12):1920. |