| Bioactivity | Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo[1][2][3]. | ||||||
| Invitro | Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic[1]. | ||||||
| Name | Hexa-D-arginine | ||||||
| CAS | 673202-67-0 | ||||||
| Shortening | RRRRRR-NH2 | ||||||
| Formula | C36H75N25O6 | ||||||
| Molar Mass | 954.14 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Hexa-D-arginine
CAS: 673202-67-0 F: C36H75N25O6 W: 954.14
Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, P
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